Familial Adenomatous Polyposis Gene

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In some cases FAP can manifest higher in the colon than usual (for example, the ascending colon, or proximal to the splenic flexure, or in the stomach or duodenum ) where they show no symptoms until cancer is present and greatly advanced. APC mutations have been linked to certain other cancers such as thyroid cancer. As the mutation causing FAP is autosomal dominant, it can be inherited directly from either parent to a child. A genetic blood test of the APC gene exists that can determine whether it is present, and therefore can predict the possibility of FAP. Individuals at risk (due to family links or genetic testing) are usually offered routine monitoring of the intestinal tract every 1–3 years for life, from puberty for FAP and early adulthood for attenuated forms. Colon resection surgery is recommended if numerous colon polyps are found due to high risk of early death from colon cancer. International polyposis registries exists that track known cases of FAP or APC gene defects, for research and clinical purposes. Mutation of APC also occurs commonly in incident cases of colorectal carcinoma, emphasizing its importance in this form of cancer.

Keywords: familial, familiale pflege, familiale pflege uni bielefeld, familiale pflege aok, familialisierung, familiale mulliez, familial cold autoinflammatory syndrome, familial mediterranean fever,


Photogallery Familial Adenomatous Polyposis Gene:


Familial Adenomatous Polyposis Gene


Familial Adenomatous Polyposis Gene


Familial Adenomatous Polyposis Gene


Familial Adenomatous Polyposis Gene


Familial Adenomatous Polyposis Gene


Familial Adenomatous Polyposis Gene


Familial Adenomatous Polyposis Gene


Familial Adenomatous Polyposis Gene


Familial Adenomatous Polyposis Gene


Familial Adenomatous Polyposis Gene


Familial Adenomatous Polyposis Gene


Familial Adenomatous Polyposis Gene


Familial Adenomatous Polyposis Gene


Familial Adenomatous Polyposis Gene


Familial Adenomatous Polyposis Gene


Familial Adenomatous Polyposis Gene


Familial Adenomatous Polyposis Gene


Familial Adenomatous Polyposis Gene


Familial Adenomatous Polyposis Gene